Mute
Ana Elisa | Farmacologia
💊 Mecanismo de Ação dos Opioides Para o profissional da saúde, entender como os opioides agem é crucial para o manejo seguro da dor. Os opioides atuam como agonistas de receptores específicos no Sistema Nervoso Central (SNC) e medula espinhal, principalmente. Esses receptores são acoplados à Proteína G (Gi/o). A ativação desses receptores desencadeia uma cascata inibitória que modula a transmissão da dor: * Pré-sináptico: Ocorre o fechamento de canais de cálcio voltagem-dependentes, reduzindo ...
Follow
1
0
0
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