Mute
Dr Jorge Yamamoto
O eixo hipotálamo-hipófise-testicular (HPT) é responsável pela regulação da produção endógena de testosterona e espermatogênese. A administração exógena de testosterona, especialmente na forma injetável, resulta em uma inibição desse eixo por meio de um mecanismo de feedback negativo. Com o aumento dos níveis séricos de testosterona, o hipotálamo reduz a liberação do hormônio liberador de gonadotrofinas (GnRH), o que, por sua vez, diminui a secreção do hormônio luteinizante (LH) e do hormônio fo
Ikuti
39
1
15
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